The Salmonella typhi IgG (TYPHI DOT) test is a diagnostic test used to detect the presence of IgG antibodies against the bacteria Salmonella typhi, which causes typhoid fever. The test is a dot blot immunoassay that involves the use of a nitrocellulose strip containing several antigenic components of the Salmonella typhi bacterium. When a patient’s blood sample is applied to the strip, any specific IgG antibodies in the sample will bind to the corresponding antigens on the strip, producing a visible dot. The presence of these IgG antibodies indicates a past or current infection with Salmonella typhi. The TYPHI DOT test is a reliable and rapid diagnostic tool that can be used in areas where typhoid fever is prevalent, and where access to laboratory facilities is limited.